
Dr. Joyce O’Shaughnessy Endowment for Innovation and Hope
Honor Dr. Joyce O’Shaughnessy’s 40 years of leadership in breast cancer research by supporting an endowed fund that fuels early-stage studies, innovative clinical trials and new options for women facing the most challenging diagnoses.
Honoring a legacy of transformative care
For more than 40 years, Dr. Joyce O’Shaughnessy has advanced breast cancer research and brought hope to thousands of patients and families. Her leadership helped establish Baylor Scott & White Charles A. Sammons Cancer Center as a national destination for innovative trials and compassionate care.
For many women, especially those with aggressive or recurrent breast cancers, standard treatment options can run out. This is when research is not theoretical — it is urgent. Dr. O’Shaughnessy has built her career around asking hard questions for patients who need answers now, designing studies that explore new pathways when existing approaches fall short.
To honor her legacy and extend it for generations, Baylor Scott & White Dallas Foundation has established the Dr. Joyce O’Shaughnessy Endowment for Innovation and Hope in Breast Cancer. This permanent source of support accelerates early-stage research, powers real-time clinical trials and helps recruit the next generation of leaders to build on her work.
Why this endowment matters
Early-stage breast cancer researchers face challenges that traditional grants can’t always address — like rapid pilot testing, data analysis and launching proof-of-concept clinical studies. Philanthropy provides the agility to pursue breakthroughs in real time.
Dr. O’Shaughnessy’s recent TRIM Trial exploring GLP-1 inhibitors and breast cancer recurrence reflects this model. With donor support, trials like these can move from concept to patient impact faster than ever.
About Dr. Joyce O’Shaughnessy
Dr. O’Shaughnessy is recognized as one of the nation’s leading breast medical oncologists. Her research, publications and clinical leadership have shaped standards of care for decades. She has led pivotal trials, authored hundreds of studies and continuously pushed the boundaries of what is possible for women facing breast cancer.
An endowed fund in her name reflects both her legacy and her vision for a future where every woman has access to cutting-edge, lifesaving options.
The Dr. Joyce O’Shaughnessy Endowed Fund supports:
- Real-time go/no-go trials that quickly generate data and accelerate progress, such as the TRIM Trial, exploring GLP-1 inhibitors and breast cancer recurrence
- Recruitment and retention of leading experts, keeping Dallas a national center for breast cancer innovation
- Hope for the hardest cases: Continuing Dr. O’Shaughnessy’s legacy of pursuing ideas for women with few treatment options.
Your impact: accelerating discovery
Philanthropy is essential to advancing this work. Your gift—of any size—helps fuel the research, clinical trials and innovations that give patients new options when they need them most.
By supporting the Dr. O’Shaughnessy Endowed Fund, you join a legacy of scientific progress, lifesaving care and leadership development.
Together, we can honor Dr. O’Shaughnessy’s extraordinary 40+ years of service and ensure her impact continues for decades to come.
For more information, contact
Featured stories
See how philanthropy advances breast cancer research and supports innovative clinical trials at Baylor Scott & White.
Intercepting breast cancer recurrence – Dr. Joyce O’Shaughnessy
Honoring the constants that carry us




